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Can You Take Phentermine Long Term?

General Phentermine Questions?
Check out the ultimate guide to phentermine weight loss pills!

While phentermine is very useful and effective in helping you to lose weight, it is important to remember that taking phentermine long term is not recommended, and that phentermine has always been intended for short-term use only. This is because of the ways in which phentermine affects your heart and can cause serious side effects, plus it can be addictive and becomes less effective over time as your body becomes accustomed to its effects. Here we explain more about why phentermine is only recommended for limited periods of time, the potential risks of taking phentermine long term, and how you can maintain weight loss without taking phentermine long term.

Why Phentermine Is Recommended For Short-Term Use

Phentermine has been available on prescription since the 1970s for the short term management of obesity after first receiving FDA approval in 1959. It is recommended that phentermine only be prescribed short-term, typically interpreted as up to 12 weeks. There are two reasons why phentermine is only prescribed for a short period of time:

– How Phentermine Effects The Body

The first reason is because of the effects phentermine has on the body. Phentermine is classified as a controlled substance, recognized as having a structure similar to amphetamine. Like amphetamine, phentermine acts on the central nervous system to stimulate neurotransmitters in the brain, including dopamine, epinephrine (adrenalin) and norepinephrine (noradrenalin). This causes phentermine to increase energy levels, suppress appetite and minimize cravings, making it an effective weight loss medication which helps you to lose weight quickly.

However, for many patients taking phentermine, the initial effects can be quite aggressive, including feeling ‘wired’ and unable to sleep, with little to no appetite and a variety of side effects, such as dry mouth, anxiety, depression, nausea, and mood swings. Over time these side effects reduce, but so do the effects of appetite suppression and energy boosting. This is because the sustained used of many drugs causes adaptation within the body that tend to lessen the drug’s original effects over time, known as drug tolerance. Many phentermine users experience a reduction in effectiveness of the medication over time, which indicates that tolerance is occurring within the body, until eventually patients experience fewer and fewer of the desired effects, with even the maximum dosage of 37.5mg providing very little appetite suppression or extra energy. This is why it is crucial to take a break from phentermine, and then only take it for a further period if it is deemed necessary by your doctor. It is not uncommon for patients to take phentermine more than once, however, it is not advisable for patients to take phentermine for several years; having to take phentermine many times would indicate that it is not effectively helping the patient to achieve long term weight loss, and so alternative treatment should be considered, such as counselling or more personalized dietary and lifestyle advice.

As a stimulant, phentermine also causes the heart to work faster as a means to enable the body to work more efficiently at processing food into energy. Over time this can put stress on the heart, which can in turn result in symptoms such as chest pains and an increase in blood pressure, among other heart-related side effects. Therefore, due to an increased risk of harm to the body coupled with a reduction in effectiveness, taking phentermine long term is not worth the risk to the patient.

– The Limitations Of Phentermine Research & Development

The second reason that phentermine is only recommended for short-term use is that the drug was never systematically tested for long-term use, and therefore cannot be considered safe when taken for longer periods of time. In the research and development stage, including clinical trials where patients took phentermine and were observed for weight loss and side effects, phentermine was only ever tested for short periods of time. Therefore, the recommendation for it to be taken for up to 12 weeks is based on the length of time that phentermine was taken for by participants in these clinical trials.  Because phentermine was first tested in the 1950s, it was not subjected to the rigorous testing methods that the FDA now impose, as shown by the extensive year-long trials into Contrave, the latest weight loss drug to be approved by the FDA. Therefore, when considering the possible effects of taking phentermine long term, we have to rely on anecdotal reports from individuals, and by inferring results from the long-term effects of taking drugs with similar substances to phentermine, such as amphetamines.


can you take phentermine long term?

The Risks Of Taking Phentermine Long Term

As we have explained, phentermine is not intended for long term use, but despite this, there are still posts on our phentermine forum from members who have taken phentermine for several years. Threads discussing taking phentermine for extended periods include reports of migraines, heart problems, high blood pressure, and one account of one forum member who, despite having a BMI of 22, is still taking phentermine after nearly 7 years and who is now experiencing eyesight problems as a result. The fact that this forum member is a healthy weight would indicate that this member has developed a dependence or possibly an addiction to phentermine, whereby she no longer needs to lose weight but is still taking phentermine after years, and now her health is suffering. One thread discussing addiction to phentermine explains how people continue to take phentermine despite no longer needing to lose weight, or due to becoming dependent on it, begin to take more and more each day to get the same effects. Phentermine has a limited period of efficacy due to its amphetamine-like structure and addicting effects, so taking it long term gives you fewer and fewer of the desired effects of appetite suppression and additional energy, and more chance of dependence and suffering from dangerous side effects.

Other threads indicate that forum members doubt the addicting effects of phentermine or consider that it wouldn’t happen to them, and while individual differences mean that not everyone would experience severe side effects or dependence on phentermine, it is undeniable that phentermine is an addictive medication, shown by the withdrawal symptoms that many experience once they stop taking phentermine. For this reason, it is important to always follow the instructions of your doctor, so if you find that your phentermine prescription does not produce the same effects, you should not increase your dosage in an attempt to manage your increase in tolerance. Doing this will only lead to a greater dependency and therefore a greater chance of withdrawal symptoms once your prescription ends. This adaptation and tolerance to phentermine is the core reason for withdrawal symptoms, as strong medication can be highly reactive and addictive to the body. Furthermore, it is important to remember that as phentermine is similar in structure to amphetamine, we cannot be sure that long term usage doesn’t harm the body in some of the ways that amphetamine does when taken long term. Since no medical trials have extensively tested the effects of taking phentermine long term, we would have to base our knowledge on the long term usage of other amphetamine-like substances, which would therefore indicate that heart damage might occur, in addition to psychological damage, or other unpredictable reactions.

Long Term Weight Loss Without Taking Phentermine Long Term

Phentermine is not a miracle pill, but rather a tool kick start to your weight loss journey, and should be used only as a means to establish a routine of healthy eating habits and exercise to continue for life. If phentermine is taken without any effort to change the lifestyle in other ways, then it is to be expected that weight gain will occur once the phentermine prescription finishes. But weight gain following the cessation of phentermine is no reason to take phentermine long term, as this will just delay the inevitable, in addition to putting your health at risk.

To avoid the possibility of dependence, while still taking phentermine, you should build yourself up to face the end of your prescription by using phentermine as a tool to help you achieve a maintainable healthy lifestyle. As part of the best phentermine weight loss schedule, as well as eating healthily and exercising, it is important to establish a good sleeping routine and to take time to de-stress and look after your own well-being and emotional needs in order to create a balanced routine whereby you can continue to lose weight or maintain your goal weight without phentermine. A great way to continue this balanced routine is to use a weight loss supplement such as Phen Caps to manage the end of your phentermine prescription. Like phentermine, Phen Caps suppress appetite, reduce cravings, and increase energy but they have no side effects and can be taken for as long as you need to achieve long term weight loss.


Have you been taking phentermine long term? If so we’d love to hear from you if you have any feedback or questions, so please comment below!


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105 Responses

  1. using this medication has changed my life, its the best energy boosting apetite supressant ever. Thers a dependecy problem. I uped the dose to feel the effect and it no longer works. I took it 9 years but quitted cold turkey for my 2 pregnancies.
    Its soo hard to stop … Im concerned i was having heart aches but i dont wanna get an addiction to my medical file so i havnt told my doctor. I buy phentermine from a private practitioner who sells them by the week supply. (Shady)

    • I searched for a post like yours! I’ve been taking this “medication” for several years (off & on). If you don’t mind me asking, how are your babies doing? Any birth defects or difficulties? How were you off the diet pill before getting/trying to get pregnant?

    • Where do you buy them if you don’t mind me asking?

      • Med clinics

      • Med Clinics. Where I live they have Doctors in the office, and they make sure you are able to take it. They don\’t want anyone with high blood pressure to take this.

    • I have been on 37.5 Phentermine off and on for several years. The main reason I take it is to keep me awake. I am constantly falling asleep. I have sleep aphea and use my machine every night but still hasn’t helped a lot. I have been tested 3 times and not too long ago they raised my pressure on my machine but still hasn’t helped much. The Phentermine gave me just enough energy to get things done that I need to do most of the time and I have never abused it. It hasn’t helped me a lot to lose the weight but it helps me not to overeat. When not on it. I eat everything not tied down. Yes I guess you can say I’m addicted to it but I do not abuse it. My blood pressure is fine even though I’m on blood pressure med but have been on the same dosage for several years. My Dr just took me off of it so got to find some more somehow. Can’t function without it. Don’t care what it may be doing to my body but I feel it’s worse without it because I have no energy to do anything. I work a part time job where I am on my feet sometimes 10 hrs a day so I need the extra boost. I think the more energy you have to do things the better off you are than just sitting around and sleeping all day which is what I have been doing

      • Same I can totally relate…I was given all manner of meds a few years ago by a consultant physician ( expensive specialist) fornFibromyalgia and ptsd ( I was shot). Only Duromine has helped and I was put on it due to massive 60 kg weight gain. Now 7 months later and 31kg lighter, my life is great and getting better..l29kg to go. Sleeping, well energy to burn and happy.


      • I agree

  2. I\’ve been on phentermine 4 months and have lost 50lbs. I initially got on it to lose weight for my wedding in May of 2015. I had a baby in Nov of 2014 so I had a lot of weight to lose. I was 275lb. I\’m a 31 yr old stay at home mom w 3 kids and lost the hope of ever being thin again. I ate out of boredom…ALL the time. My fav thing to do was get as stuffed as possible on the most junky crap I could find then take a nap! I felt hopeless. Phentermine jump started me like nothing else. The first 2 wks I was NEVER hungry, the thought of my fav foods lost all appeal!! I had to make myself eat only cause I would begin feeling dizzy from not eating at all. Even then I could only eat a few bites. After the 1st two wks I began getting that hungry feeling about once a day. No cravings for junk though. I actually wanted salads & baked chicken! I don\’t know (or care) whether it was the rx or my will power I WANTED to eat differently. After the first 25 lbs I began working out & the rest just fell off! Great tool to kick start ya, but I will say after 4 months the effects are much less. If I hadn\’t changed my entire lifestyle w working out & eating healthy I would\’ve already began gaining weight. I mostly take it now because I\’m scared I\’ll gain it all back if I stop.

  3. Can phen be broken up to take every other or 3rd day? I\’m loosing almost 20# in the 15 weeks on it. I\’m already not taking it on the weekends, since starting this last go around, I\’ve used it 20 months ago and lost 30# in the 12-13 weeks, but was taking it every day, back then. Main reason to take it now, was hernia surgery and no way to really exercise.

    • Hey Bridez, it’s best to ask your doctor about taking it less often than prescribed. It could certainly help to wean you off it if you’re about to come to the end of your prescription but I would just check to make sure.
      Sally, phentermine.com

  4. I\’ve been taken phentermine for 17 months now. I have acid reflux and have had it for yrs. I take 30mg of Prevacid twice a day. My stomach is getting real bad to the point I\’m afraid that anything I eat or drink will upset it. Just a thought if this could be contributing to the problem? I am also a diabetic. That has gotten better though.
    Thx Kim

  5. I have used phentermine on and off for 15 years, managing my own dosage. My dosage is very high at this point and believe its seriously effecting my health. I have been able to deal with the side effects until recently. I\’m experiencing many new issues, ranging from foggy head to sore muscles to skin rash to vision issues, etc. I worry I have permanent damage. I\’ve known for awhile I exhibit signs of addiction, I have never been able to stop taking them for good. I think its alarming.

    • Hi RLB,
      Thanks for sharing. Your story shows the dangers of taking short-term drugs for long periods – we urge you to see your doctor about this immediately; risking your health for phentermine isn’t worth it. Please at least confide in someone you trust to help you through this to find a way out.
      Good luck,

    • I completely empathize with you!! Its so crazy how these pills have a hold and makes matters worse that these doctors who name is on the bottle may see you once for 2 minutes and never again. I will have you in my prayers as I am in the same boat almost 18 years later.
      Did you, were you able to stop?

  6. I initially took phentermine for a kick start to my weight loss but found that it helped my ADHD symptoms and I\’ve been on and off it for approx. 5 years. I have tried close to 20 other medications over the years for my ADHD but phentermine is the only thing that works for me. (Note: as was stated in the article, the appetite suppression is no longer there.)

    Going through peri menopause now it helps with my brain fogginess and depression.

    • I have been searching and searching for people that feel the same as me. I was on it off and on (prescribed by the Dr on off) and lost 50lbs…my life was amazing on it. BEST antidepressant ever. I wanted to do things socially i never had before…i felt confident and happy…no anxieties…i could breathe better…like it opened my nose to smells…my body didn’t ache to move…I WANTED to move and stretch like a new born baby giraffe. I can only explain my love for my new best friend as THANK GOD i finally all my life feel comfortable in my own body…and i was wanting to finally live!!!!…..then i got off them 😟…..now there’s fogginess…EXTREMELY DEPRESSED….like cry all the time and don’t want to get out of bed for ANYTHING. I’m 42…maybe premenopausal….history of depression in the family…I’m talking to a new Dr now and hoping to find me again. But my research so far….why not give me this… Adipex was helping me with pain in my joints…no more feelings of self esteem that i hated feeling everyone that looked at me judged me..there’s SOOOOO many medications that have worse side effects…i need more studies done of the WAY more benefits then just energy and weight loss…I’m happy i did lose the weight….but i was more happy with the confidence and anxiety loss i felt

      • I feel the same way. I have been on and off for almost a year, so the appetite suppressant still works, but I often have to stop taking them for a few days and start agsin to have it kick back in. Anyhow, I love all the other benefits I seem to have. It has helped with my ADHD and my confidence. I worry about every bad effect it can have, but not enough to stop yet.

        • Are the phentermine capsules safer? Does anyone know? I’ve been on the tablet off and on I use to loose weight to bring my A1C down so I won’t get diabetes, I am borderline. Phentermine helps me in that way

      • I have been taking phentermine for about 3 mths. And like you i find that it helps my depression also i havr osteoarthritis and I dont hurt when i take it. My narcolepsy completely disapers and I no longer have to take meds for fibromyalgia or neuropathy. That to me makes it very worth it as phentermine is the only thing that I\’ve found that actually helps

  7. I took phentermine for about 5 months. I had extreme dry mouth and notices that I had developed a nervous habit of constantly moving my lips and tongue. I am becoming very aware of doing this weird constant movement with tongue and mouth and becoming very self conscious. I have been off for three months now and was wondering how long this tick / nervous habit will continue.

    • Hi Kim,
      Thanks for getting in touch. We haven’t heard of anyone developing this kind of habit. Do you do it now when you are thirsty or have a dry mouth, or is it more random? The best way to try and stop doing it would be to get people close to you such as friends and family to tell you when you’re doing it if you’re not always aware of it, then you should gradually do it less and less.
      Hope that helps!
      Sally, phentermine.com

    • I know this is an old post put I too have this issue with my lips

      • I am constantly grinding my teeth or some type of mouth movement as well. Chewing gum helps.

        • I\’ve only been taking it for 2 days and already my tongue is sore from rubbing the inside of my teeth. I remember doing this last time I took these as well.balso when I lay down to sleep at night my leg muscles are so achy it\’s almost impossible to fall asleep.

  8. I’ve been taking phentermine for three years now and it’s lost its effectiveness .. I needed to lose 15 lbs and I achieved that but every time I try to quit taking them I feel so sluggish and the weight starts to come back on .. the sluggish part is unbearable cause I can’t concentrate on my job . I HAVE to go back and get some more which I believe I’m addicted. Even though it’s lost the effect to lose weight it still helps a little with the energy.. And that’s not as good as it once was. I just can’t bring myself to quit. I thought of taking a second dose but that would only make things worse.

    • Hi Cori,
      It really does sound like you are addicted to phentermine. You need to talk to your doctor about getting help and weening yourself off the medication slowly, or perhaps there is something that you can take to help you with this process. Please speak to someone about this, it’s not normal to need to rely on a weight loss medication to concentrate on work, you may have an undiagnosed condition which your doctor can help you with.
      Sally, phentermine.com

  9. I\’m 34 been taking phentermine for 4 years I try to stop from time to time but I start over eating and go back right away. I been buying it in Mexico so no doctor has ever prescribe it to me. I do annual biometrics check ups and I come out normal none of my family members know I take phentermine. Don’t know how to stop and find a better way to lose weight. HELLLPPPPPP

    • Hi Breloza,
      We would really recommend that you speak to a doctor as it sounds like you need to be referred to a counselor or psychologist for overeating and for your potential addiction to phentermine. If that seems like too big a step, please just speak to someone you trust to be helpful, objective and non-judgmental to help persuade you to see someone or to support you during this time. Best of luck.
      Sally, phentermine.com

    • Do you mind me asking how do u go about getting them in Mexico? Is it a site you buy from?

  10. I have been taking this drug for the last 4-5 years off and on for periods of time shorter than 3-4 months at a time. I want to take it again to jump start my weight loss once again. Am I at a great health risk?

    • Hi Simone,
      Thanks for your message. Taking it now and again over a longer period of time certainly has fewer health risks than taking it continuously, but it’s not ideal to need to rely on phentermine to jump start cycles of weight loss before you then put it on again. It would be better to establish a routine of healthy eating and exercise which you could maintain over time and then not yo-yo between weights. I would speak to a dietitian or your doctor to see if there is a program they would recommend so that you don’t have to keep taking phentermine.
      Sally, phentermine.com

  11. I’m mid 40s. I initially took phentermine to lose 20lbs and to help relieve lower back pain (weight in my stomach). During the first year, I dropped 33lbs–the weight melted away. I eased off the dose and gained back 15lbs. I’m now very comfortable with my weight, I do yoga, physical therapy, and walk several times a week. I continue to take 1/2 dose a few times a week to help take my food cravings away–it still works for me. The only side effect is dry mouth. I also take 1/2 dose of a water pill. Sometimes I get headaches–Tylenol helps. I’m entering my 3rd year on this regimen and under a doctors care. It has helped me maintain my current weight and gives me energy to exercise. The combination has done wonders for my back pain….I’m thinner, fitter and can deal with the minor side effects….am I addicted? maybe, but the pros outweigh the cons.

  12. My doctor started me on Phentermine in May 2015. I never take any medications of any kind so I was very skeptical to start. But I was close to 100 pounds overweight. A 30 year old, 5 foot 5 inch, female shouldn’t weigh 248 pounds. I was desperate. When I first started, I was feeling great. I could hardly eat anything. I didn’t see any results until after about a month and a half. I have been on it now for 8 months. My total weight loss is around 60 pounds. I took breaks from it. Still there are some days that I just skip. I know I am not addicted because I can go weeks without having it. The only reason I continue to take is simply because I am scared that I will gain everything back once I stop. I have changed lots of my eating habits and I exercise regularly. If I give it a rest, say a week or so, then start again, I get the full effects as if I just started. The only side effect that I seem to have is constipation. I don’t want to take this medication (or any medication for that matter) for a long period of time. I do still have about 50 pounds to lose, so would you recommend I continue taking it or try something else?

    • Hi Carrie,
      If your doctor is still happy to prescribe it then I would say that it’s safe for you to take it to reach your goal, especially as it remains effective for you and doesn’t cause too many side effects. If phentermine were a new drug then it would most likely be tested and approved to be taken for up to a year, but since it was first approved in the 1950s, when people had less weight to lose in general, I assume they didn’t think it was necessary to test it for so long. I am interested to know what happens when you stop taking it though; do you continue with your good habits, and do you still lose weight? Or do you find yourself slipping back and gaining weight? This is the true test of whether you will be ok moving forward without it, so maybe you could make it your aim to concentrate on establishing permanent healthy habits that you can still maintain even while you’re not taking phentermine for those weeks where you give yourself a break. Good luck!
      Sally, phentermine.com

  13. I have been taking phentermine off and on for years. Everytime I stop, I go back to bad eating habits and the weight comes back. I am afraid that I could be doing unseen harm to my body. I was wanting to know if anyone else has seen the effects of long term use of phentermine. I’m not addicted because I stop periodically, but I think I have experienced withdrawal symptoms: low energy and fatigue. I am on the verge of going to get more because I’ve put on weight, but I’m more afraid of what I could be doing to my body than the weight.

    • Hi Susan,
      It sounds like phentermine isn’t really working for you in the long term – you might respond better to another form of weight management such as counselling or a permanent diet plan. I would ask your doctor if there is anything he or she can recommend which would allow you to lose the weight and keep it off. Good luck!
      Sally, phentermine.com

  14. Hi I’m 26 and have been taking it on and off for about 5 years now. Realistically I’m not over weight at all but I can’t come off of them. I’ve also noticed my eyesight deteriorate over the last 2 years but most recently has gotten really bad to the point where I’m considering laser surgery….I’ve never in my life needed glasses and now I’m considering laser surgery…. is it possible for the pills to effect my eyesight like this?

    • Hi Dee,
      The changes you’re experiencing may have happened anyway as your eyesight can change throughout your life so needing glasses when you didn’t before isn’t in itself very unusual. However, phentermine does affect eyesight, and it is a problem we have seen more references to when people take it long term. But the real issue here is that you sound like you’re addicted to phentermine, which is something that you should discuss with your doctor to see if there is some way to come off it for good. Your eyesight may even begin to improve if you stop taking it, so it is certainly something which you need to address, for the good of both your mental and physical health.
      Good luck!
      Sally, phentermine.com

  15. I am a 36 year old female. I was having lots of trouble with weight gain. It seemed when I hit 30 BOOM my body quit working like it used to. My Doctor and gyno checked blood work for an array of possibilities mostly thyroid. I was all clear. After a few years of trying everything I could with diet and exercise, I felt hopeless. So my doctor prescribed phentermine AS directed for 3 months. It worked! Lost 25-30 pounds. I managed to do great for months especially through the summer when I could be more active. About a year and a half later.. BOOM hit again… struggled terrible to get it off. Still convinced I had thyroid issues we do MORE blood work…. nope… all clear…so I ask to be put on again. My Doctor allows it for the DIRECTED use of 3 months. Amazingly it works. I never felt dependent on it. I was also directed and educated about the prescription thoroughly.So I feel maybe I was more aware of what to be aware of. I also felt it was a last hope, and I needed to do the work. It’s not a “miracle pill”
    The only true bummer for me was I felt it did make my mind feel “right” …. I felt my brain was finally working properly. I felt clear…. as to when I had tried over my 36 years 4 different types of antidepressants which made me 10× more depressed… they now scare the heck out of me and I will NEVER try that again. So is there a reason my brain would trigger like that? Almost a reverse effect?

  16. I have been taking phentermine 37.5 and b12 shots for a year and I have lost 60 llbs total. However for the past week my hands and arms keep going numb. It feels like pins and needles all the way up to my elbows. It is so uncomfortable and it’s pretty constant. Also it’s not from repetitive use of my hands and arms so I am so nervous. I plan to make a doctors appointment next week. Has anyone had similar issues from taking phentermine? I am scared because it just started out of no where and it’s just really painful. Plus I didn’t get it from a normal doctor it was from a chiropractic office who offered medical weight loss..

  17. Hi there… I started taking Phentermine 5 days ago. I have now become a little bit scared because I felt like my head was being squeezed a little bit by vice grips. I also had really bad diarrhea and I felt like my jaw and legs were jittery. I was scared to take my pill this morning because I didn’t know if this is the beginning of something serious because I have read a lot of scary things from the side effects but I have also read a lot of good things about the medicine as well. I didn’t know if maybe this is normal and it just takes a little longer to kick in but I’m so scared and confused right now but I have been very unhappy with my weight and as right now I am at 313 pounds and I’m only 29. I have a low metabolism and I was hoping this would really help especially with curbing my appetite….

    • Hi Kimberly,
      Unfortunately these side effects are all quite common with phentermine, especially when you first start taking it. One tip that many people find useful is to start off with half their dosage to help their body get used to the effects, and then they are usually able to work up to a whole pill within a week or less, with reduced side effects.
      Hope that helps!
      Sally, phentermine.com

  18. Hello,
    I was on phentermine for almost 30 years with a couple of breaks of maybe a year or two within that time frame. I stopped taking it August 2015 and I am now experiencing shortness of breath.
    I have had an abnormal EKG which shows tachycardia. I am scheduled to see a cardiologist on April 11 and I am petrified of what they are going to find. Thank you for listening.

    • So, what happened?

    • Please tell us what your results are?

    • I have been taking this for 17 almost 18 years and I regret the day I ever started!!! Yes it gave me the chancce to be super mom, super wifey, work and have enough energy to work out 4 times a week. I went dow to 9% body fat a size 2 from a size 13 but God as my witness this addiction isnt worth it. I had kidney stones super large ones and then a ridiculous amount of gallstones that was so painful until my insurance approved removal. I have lost almost all the cartlidge out of my nose….I could go on. Let me tell you that bad circulation and dry mouth with the occasional mood swings are nothing if you continue to take this. I pray all the time that I will stop I have tried many times for years. The dehydration makes my skin look bad so I pay for the highest quality hydrating lotions and scrubs I can. My memory at 43 is obviously been affected. I used to be know for my “blessing and curse” as I could and would remember everything. Well, not now. I know its the pills that have caused this. I am so tired if I don’t take them and its so obvious its chilling. I stopped with the pregnancy of my second daughter and while she was born normal she never slept the hours my first 2 kids did before the pills and years later she is still so hyper compared to my other girls. She is always hungry and sadly has a weight problem. It could be coincidental but being just 3 years difference in age it always makes me wonder. I found out I was pregnant at 3 months because mother nature didn’t stop. That was another weird new thing. If I could tell anyone to stay away from these I would. I have never, ever spoken about my addiction because I am too ashamed but now I worry about my health and the fact that I literally feel that I don’t have enough energy to stay awake and perform normal activities without them. P.S I have gained 40 pounds in the last 5 years and taken them all the while. Yes I did take the 3 months breaks several time to get them to work but they only gave me the energy. I cant even imagine breaking now. Makes me sad the hold they have on me.

      • Regrets…

        Are you still suffering in silence…? I too am 17 years and still haven\’t accepted. To even confess to my Hubberoo, BFF or GP would be unheard of in the UK. Us \”Brits\” are known for our stiff upper lip and \”keep calm & carry on\” attitude. I no longer benefit from weight loss… just about maintain my womanly curvature. I just cannot function without. Energy, lethargic and a can do attitude disappear so I result to what I know. What started off as a short term fix to accept being dumped by a 10 year relationship has turned out to be my secret love affair… it\’s my secret… only I now know it\’s long term effects. Heart, anxiety, insomnia, confused and confidence are on my long list… if only, to turn back the clock. Never shared or opened before. Be kind I am vulnerable… I pray no one suffers or feels the same…xXx

  19. I started taking phentermine 1 year ago, I am currently 37. I wanted to lose 20lbs. My problem is food. I’ve always been on the thin side (maybe high metabolism), but I eat crap food. A lot of fast food… cheeseburgers are my downfall. While others have a sweet tooth, I have a grease tooth! LOL. I’m 5’5 and was 150lbs when I started the drug. I had 3 kids in 2 years (yes, one set of twins) and even though I lost all of my pregnancy weight, very quickly after delivery, it didn’t take long to gain more than half of it back. I am a working mom and I don’t make time for the gym, or I’d never see my kids. I went to my doctor with the question of would taking an over the counter appetite suppressant negatively affect any of the current medications I was on. He said he didn’t know enough about the one I mentioned (that a personal trainer friend was taking and recommended) but he could prescribe one to me that he had been prescribing to patients for over 30 years. My first month on it, I lost 13lbs. 2nd month, I lost 8lbs, 3rd month 6lbs and 4th month 2lbs. After the 4th month, I didn’t lose much more. I fluctuate 3lbs, depending on the time of month. So my weight ranges from 117-120lbs which puts my BMI in the normal range. I had a little trouble sleeping at night, but on those nights, I would take Benadryl and be knocked out. Those first 4 months were amazing, I gave up soda the first day I took it with no “withdrawal” headache. I drank so much water. I was a little worried about how not hungry I was so I knew I had to force myself to eat to be healthy. Only the first month or two was like that. Then I gained an appetite, but it was small. After the 4th month, I didn’t really notice the drug working anymore. The only thing I did notice was that I was able to function throughout the day without feeling tired or sluggish. Even if I was on a few hours of sleep. I asked my doctor to let me stay on them and if it would be bad. He said since I don’t have high blood pressure or any negative side affects, he was ok with it. I haven’t lost any more weight, still maintaining the 117-120lbs range, which is totally fine to me. I have a normal appetite, just not my crazy eat all day one that I previously had. I want to stay on them, for the simple fact that I’m afraid that if I go off them, I will just gain all the weight back. Is that an addiction? I’m not sure… I don’t smoke, I rarely drink. I eat a lot of processed foods. I would say that I’m a fairly healthy person but I don’t have the confidence that I can do this without the drug. I still eat out often. I just don’t eat as much in a day as I used to. And I attribute that to the drug. I wish I could know what other things I might be doing to my body by staying on it. I don’t want to lose my sight or any of the other crazy things I’ve read. But I also don’t know what other things those people have going on. Comparing myself to others could be like comparing apples and oranges. I am just going to trust that if my doctor had a concern, he would take me off of it. I’ve been seeing him for almost 20 years. Just wanted to share my story and say thank you for taking me back to my weight from high school. I feel amazing! 🙂

  20. I have been taking Phentermine off and on for 2 years and I’m convinced that it’s causing me to have Kidney stones. Phentermine has a tendency to make you dehydrated and if taken without the right amount of water intake each day, I believe that this is causing my kidney stones. I am going to stop taking the medication immediately. Has anyone experienced Kidney stones?

  21. Hello I have been on phentermine now for 2 years, quit cold turkey once for 3 months just to see if I could. I started out at 250 pounds at 5’4. I have lost more than 80 pounds now! My doctor has me on a combo of phentermine and Topamax. So far it’s worked great for me! When I went off it for 3 months I slept all the time I wasn’t going to the gym or getting up near as early and of course my appetite increased! What I am going to do at the end of this month when I start to slowly decrease my medications is take supplements of vitamins and vegetables and drink lots of water and exercise at least 5 times a week! And get plenty of sleep each night! This is so important while you are winging yourself off the medication. I read a lot of comments about people struggling with constipation and I would always eat a lot of prunes or cantaloupe that always helped me. With phentermine you need to take extra fiber in your diet. So that your bowls will move or you will be in trouble quick😫

  22. I started taking Phentermine a few years ago to bump start weight loss. I only took it for 12 weeks and lost a few pounds. But what I found was that Phentermine stopped my fibromyalgia pain. Completely. I started taking it again this year..in January. I have lost quite a bit of weigh this time….but by far the best thing is that I am pain free. My Dr and I are going to work on a plan so that I don’t keep losing weight so that I can continue taking it for pain relief.

    • I use marijuana to bring my appetite up

  23. I just read this article and I have been on phentermine for two years. I was 220 pounds and now I’m 135-138, it always fluctuates. The first agreement before starting this medicine with my doctor was to stop when I reached 150 pounds but I talked him into 130 pounds. So now that I’m finally the closest I’ve ever been to reaching that I can tell you I agree with the fact that this medicine SHOULD NOT BE USED LONG TERM!!! I’m very addicted like I see/hear myself get mad when there is a chance that I’m not going to be able to see the doctor to get a new script. When I ran out before I would be like I’ll just see about getting an appointment sometime later that week. Now I’m like I have to have it or I’m going to be hungry. The past two weeks I discovered I now have really bad anxiety I haven’t really eaten at all. I’ve maybe consumed 500 calories at most on a good day. But I go to the gym and burn those off. I’ve lost so much weight I wear size small shirts and a size 3 in shorts all my friends are like oh you look so good what diet plan have you been doing and all the compliments over the years make you want to stay on this medicine because you have to keep looking good, you have to have the attention… That’s the other thing, I’m addicted to the attention… Your mindset is I look good now why aren’t guys looking at me why aren’t they talking to me… I only got this guy because I looked this good so I have to stay this way or be skinnier. I CAN’T GET FAT AGAIN!!! THAT IS WHAT THIS MEDICINE DOES IN LONG TERM ASPECTS!!! Currently I’m considered anorexic but I hide it well and people don’t ask unless you tell them and who’s gonna tell them? I also agree that no the phentermine is not working and in the past two weeks I’ve added hydroxycut h2o with it is why I don’t eat anymore however I don’t recommend that either because when you do try to eat since you get shaky and dizzy and tired your stomach will twist and turn and hurt so bad because it’s not used to having food. Do it the right way people diet exercise and short term uses of phentermine only if you choose to use it.

  24. I’ve always had issues with my weight. I remember weighing 100 pounds in 2nd grade, 280 in 8th grade and 421 in 2008. In March of 2015 I decided I need to make some changes and after not seeing my doctor for 7 years and despite being a ticking time bomb. I joined the gym and made an appointment to see my dr. I began working out I don’t know what my starting weight was but I’m sure it was significantly higher than 421 from 7 years earlier. My doctor had never been able to weigh me in office. I could only find out my weight by going into urgent care or the hospital as they had higher capacity scales. By August 2015, my clothes were noticeably looser and face smaller. I was around 390. In December I had to have a minor surgery and was 374. In April of 2016 I was 371 despite working out 4 times a week 2 hours per session. A year earlier my gave me the information leaflet for qsymia. I was nervous about the side effects but after the death of a family member due to heart issues due to weight I decided I needed to get this weight off as quickly as possible. I started phentermine and topiramate in May. I went to the dr in June and they could almost weigh me. This past Friday in July they could I’m down to 349. I’ve lost 25 pounds this is my 3rd month on the drug. I have noticed some mood changes but nothing I can’t deal with. I’m wanting to lose another 100 pounds. This drug has been a godsend I really felt like I had plateaued despite meticulous tracking of my meals for the last 500 days and intense workouts. I know once I hit my goal I’ll be able to maintain with diet and exercise. I love working out and how it makes me feel so I never think I’ll be a prisoner in my body again. I think for short term use this drug will be ok for me. I think by years end I will be able to come off of it.

    • Hi!
      Thank you so much for your story, it’s great to hear how the phentermine and topiramate combination is helping you. We’d really appreciate it if you could leave a review for us here: https://www.phentermine.com/reviews.htm to share your experience and feedback with all of our readers. Good luck!
      Sally, phentermine.com

  25. Hi..read some of your comments and do agree…this phentermine is very addicting. I am ashamed to say I’ve been on it for 4 years. I want to stop, but when I do, I feel so horrible I just start again. I know I’m addicted, but like one gal said, I’m embarrassed to tell anyone. Tomorrow I have to have a colonoscopy and Dr. Told me to be off of it for 2 weeks because of the anesthesia I must have. Well, I couldn’t stop for 2 weeks….now I’m scared to have it done. I don’t want to die over this stuff.

    • Hi Valerie,
      I really think you should tell your doctor that you weren’t able to stop for two weeks. Yes, it will be embarrassing and difficult, but this is nothing compared to putting yourself at risk with a surgery which might put you at risk. If you can’t get the words out or can’t face your doctor, trying writing it down or sending an email or text message. Your doctor will be glad you admitted it rather than lie and say that you did stop the phentermine, and it could be a good way to get out your secret and take steps to getting help.
      Sally, phentermine.com

  26. I have been taking phentermine (highest dosage) for a year or two 1/2 a pill a day during the work week. I usually only take it during the week for energy and it helps with my mood. How bad do you think this is affecting my heart?

    • Hi,
      We’re not medically trained so it’s hard to say, but it sounds like you’re taking phentermine unnecessarily if it’s not even for weight loss, so you could be addicted to it. You should speak to your doctor about coming off it and finding other ways to help with your mood and energy levels, such as prescribed exercise, meditation, dietary advice or stress-management techniques. You could also ask for a check-up for things like blood pressure etc if you’re worried about your heart.
      Sally, phentermine.com

  27. I’ve used phentermine for 3 1/2 years. I received it through a clinic. I had few side effects dry mouth, some restless sleep. My energy went through the roof. I finally lost weight. From 214 lbs to 156 lbs. I felt & looked better than I had in years. My only regret is not receiving it by a regular physician to be monitored closely because there where hidden side effects popping up that I did not consider were from these pills. A clinic from my previous employment had taken me off because my feet & legs where swelling. He couldn’t believe I had been on them for so long. Since I’ve quit taking them my life has turned around. I’ve quit 3 jobs in 3 mths. I had previously held my former job 20+ years. Since I quit my last job I can longer go to the clinic. I have no dr, no insurance & I’m fighting this addiction by myself. I’m still phentermine-free although I have days I don’t think I can make it. On those days I think how far I’ve come & that helps me have strength to stay free. I’ve done some online research & this is just my personal opinion of how I think the drug has effected me – I called it my wonder woman drug, these are symptoms I suffer from since I started taking phentermine: Anxiety disorder, panic attacks, bipolar disorder, sexual hypocrisy (nympho), exhibitionist. Like I said this is just my own analysis. I also think I need a psychological evaluation. I’ve always pride myself on being strong & independent but my struggles are real. I act on impulse more now as before I would think things through. My finances have suffered because I can’t seem to work for long at a time now. My patience is short fused. I need help but without insurance or the finances I’m unable to find help. If anyone knows how or where I can receive treatment please let me know.

    • Hi Debra,
      I’m really sorry to hear about the problems you’ve had as a result of taking phentermine. Without a doctor to go to, all I can suggest as a way to ask for help is to contact an addiction helpline or go to a free clinic, and then explain your symptoms to see if there is some kind of addiction management or evaluation they can help you with.
      Good luck,
      Sally, phentermine.com

  28. After about 10 months of using phentermine I have developed hypertension. I haven’t taken any phentermine in a few days. I was wondering if my blood pressure would eventually go back to normal or is this permanent?

    • Hi Jesse,
      We’re really not qualified to say, this is something you should speak to your doctor about.
      Sally, phentermine.com

  29. Feeling all alone here! I haven’t read anything that describes my situation…I’ve never had a weight problem growing up, I’m not obese now, and I\’ve been taking Phentermine (37.5) for about 3 or 4 years (Yes, you read that correctly). I grew up with healthy eating habits & was very active in sports. I’m 49 years old, had 3 children, eat very clean, and still very active (scuba dive, ski, etc). So why did my endocrinologist prescribe me Phentermine? I had weighed about 130 lbs (I’m 5’5″) and had gained about 15 pounds without changing what I eat and under no stress. I found out that I am Insulin Resistant and was given Metformin for my glucose-insulin war, and Phentermine for the weight. I started off with half a tablet of 37.5 mg, then it was upped to a full tablet when that didn’t work. Fast forward to today, I have celiac disease so I still eat very clean but, my weight usually hovers around 140 lbs – 142 lbs. This 10 pounds won’t go away & makes a big difference in how I physically feel and how my clothes fit. If my physical activity slows down, I start gaining weight (my metabolism and thyroid were checked again and they’re fine). Can I be the only person who actually gains weight while on Phentermine?? My next appointment is in a week & I’d like to start weening myself off it if since I’ve been on it for so long & I’m worried about the effects from long-term use, and it never worked for me in the first place. Any advice would be greatly appreciated!

    • Hi Lauri,
      I’m sorry you haven’t found any advice for your situation on our blog but we mainly aim at people taking phentermine for weight loss, and yours is more of a specific individual case. We agree that it is a good idea to try and stop taking phentermine though, as, like you say, it’s not even working so it makes no sense to continue taking it. Good luck for your appointment and I hope that you can find a solution to your problem.
      Sally, phentermine.com

  30. Hi everyone,

    I started phentermine back in 2012 after I had gained almost 70 lbs during a pregnancy that ended in miscarriage. I gained so much weight because I have Hashimoto’s thyroiditis and my body just couldn’t take it. So I changed my lifestyle and phentermine has a lot to do with that. I couldn’t believe how much energy I had but more than that, I was focused more than ever not to mention the weight loss. Unfortunately, I have become dependent on it and it’s not really helping with cravings anymore. Also, I think it’s affecting my health; when I stop taking it, I get dizzy spells and feel really faint and tired. I haven’t taken them for about a week now and I’m going to try really hard to not fall back into them. I am going to look into something to help with focus and concentration, I really have been using it for that over the last couple years. It truly is a wonderful medication but I highly recommend only using it short term and sticking to a healthy diet and regular exercise regime, phentermine is an excellent spring board.

  31. I’m 46 and have taken phentermine for 8 months. The truth is that I love it! I have no side effects and I think it’s great how well the appetite suppression works. I do stop taking it for a few days at a time so that it still remains effective. My doctor said I can’t take it long term, but why not? I think it works great with my body chemistry. Is there something similar that I can take longer for weight loss maintenance? If I do start to experience negative side effects than I would stop taking it… but right now it’s still working well for me.

    • Hi Julie,
      Medications like phentermine aren’t designed to be taken long-term. You may not have any side effects yet that you know of but taking medications such as phentermine on a long-term basis are dangerous and can do lasting and irreversible damage to your body. Read some of the comments on this blog article or on our forum to see how people have been affected by long-term use. If you’re taking phentermine and no longer need to lose weight then you should take steps to come off it.
      Sally, phentermine.com

  32. I have taken this medication for almost 5 months. I have had bad headaches and it has effected my eyesight. Even now I have stopped taking the drug my eyesight is extremely bad. You never know how it will affect you or when it will start affecting you. Not a miracle pill.

  33. I have Hashimoto’s so it’s very difficult for me to lose weight. Even with going to the gym and eating right, the weight was not moving. I started taking Phentermine 2 months ago, I am on my 3rd month. I have dropped 18 lbs. so far. I plateau for days and then I drop a pound. I rather do it slowly instead of dropping super fast.

    I find that if I forget to miss a dose (mostly on weekends) I find that I really don’t miss it. However, I do nibble a bit more and ask myself why only to find out that I forgot to take it. I also noticed that I don’t crave sugar anymore like I used to but, I do eat a Power Crunch Choklat after lunch. I used to eat one after dinner but no longer do.

    My appetite has changed considerably. I don’t eat as much as I used to. I’ve been on a GLUTEN Free diet for over 3 years and when I started with phentermine I’ve been on a Low Carb, High Protein diet. I’ve cut out all processed foods. I did notice that when I do cheat, for example; I ate a Gluten Free Lasagna the other day my stomach was not happy.

    I’m glad I found this site as I was told I could be on Phentermine for 6 months and off several before I can go back again. I may just finish this year out as the holidays are approaching and ween myself off of them completely and continue with my new eating habits.

  34. I’m 52 years old , I started taking 37.5 phen my fist time 2 1/2 weeks ago.
    I’ve experienced lots of energy, no appetite, insomnia, some headaches, not to mention extreme dry mouth and constipation.
    My doctor said he would only prescribe it for 3 months just to give me a kick start. I have to say so far I’ve dropped 15 pounds, without trying to diet but staying under a certain amount of calories daily including working out 30-45 min a day.
    I’ve started my journey at 317 pounds , I began to diet and exercise before I began my phen. I dropped 35 pounds on my own in 3 months. Then my next doctors visit I gained 12 pounds back, I was very upset so my doctor told me about phen. I went from 294 to 278 in less then 3 weeks. I want to stop taking it because of my side effects but I’m afraid I will gain it back. I think people should be able to try it as a quick weight loss for a short time without bad side effects. Until you’re ready to see a difference with the pill and the long term damage or stop and think twice about what’s better for the long run doing it the healthy way. My goal is to lose 130 pounds at 5’6″ without meds and doing it slow with the right diet and exercise for long term health.

  35. I’ve taken phentermine on and off for ten years now (since 2006). A co-worker introduced me to them after I complimented her on her weight loss. I was in my mid-twenties, already exercising some, and vegetarian.

    It worked wonders and I had tons of energy and excitement about life and could find lots of deals on size small clothing on the sales racks. It was a golden time.

    I only stopped taking them during periods when I switched jobs and made a lot less money (@that time, I paid $25 for a visit at the doc-in-a-box, botox/”spa” place, $100 for the pills, 37.5mg, 30ct). I would regain most of the weight. At my smallest, I wore a size 2-4, weighed a muscular 139lbs for my 5’4 height). Glorious times indeed.

    When I found a cheaper place, an ob/gyn who also ran a weight clinic and charged $20 & wrote an RX to be filled for only $8 at Sam’s, I started back. Each time I’d do this, the weight would melt off again but not quite as easily. I sometimes wondered if the Adipex was a diuretic because the first day I took the pill, I’d pee maybe 12 times and the next morning, I’d look 5lbs slimmer instantly.

    Again, each time I started back up on the pills, it worked BUT I began to depend on it more for maintenance of current weight and energy (much better than coffee, wouldn’t stain my teeth) & less for new weight loss and fitness goals.

    After being on phentermine for about 2 years straight between mid2014 – mid2016, I stopped cold turkey.

    OMG. It was ridiculous. Since July 2016, I’ve gained 35lbs. It’s only the beginning of November. I’ve experienced a profound loss of energy, motivation, positivity, willpower… I am having a difficult time deciding what is depression due to withdrawal versus other situations in my life. I can’t tell how much of the weight gain is due to hormonal changes because I’m getting older (35) versus withdrawal. I’ve even been reevaluating what I know about my personality (just how much of that “joie de vivre” over the last 9 years was due to my own unaffected bubbly nature versus…phentermine highs?

    In the past two months, I’ve considered going back on the pills just to get my weight under control (who wants to have to buy new “big girl”clothes?)… But I cannot. I’ve fought too hard to get my mental state back from that abyss. And, boy has it has been abysmal–again, I kept going back and forth between feelings of healthy grief/PMS-y type days and wondering what the heck was wrong with me, I’m fat, ugly, worthless and gonna lay here and not do anything about it. Miserable.

    I do NOT recommend phentermine, short or long term use. I did not mention earlier how I also worry that I might have developed a heart issue (and I’m almost terrified to get that checked out). It’s addictive– you’ll crave the mental stimulation/energy boost and become spoiled by the unrealistic fast weight loss results with little effort. Long term, the cost adds up and the benefits are soon outweighed by the pounds you pack back on as soon as you stop taking it (doubly so if you didn’t bother to modify your eating and exercise habits).

    I survived 10 years (mostly on, sometimes off) of Adipex /Phentermine. I weigh more now than I ever did (a whopping 193lbs) and I wish I’d dedicated more time to learning how to do better the right way. Hope this helps someone!

    • Hi Nik,
      Thank you so much for sharing your experiences of taking phentermine long term. We really appreciate your honest account of how phentermine has affected you, and we hope that you get the help you need to overcome the problems you’ve faced since quitting. Good luck.
      Sally, phentermine.com

  36. I am 47, have been on phentermene for almost 4 years now. I started taking it to lose 20lbs so I’d look & feel better (for pictures!) for my son’s graduation… the first couple years were great! I had energy, worked out, was proactive and driven at work. Was the fun spontaneous mom! Even better – I had a lot more energy and confidence in the bedroom for my husbands sake ! I was losing weight, felt great & looked good. I did get the dry mouth, constipation, headaches and insomnia – but all the pros outweighed the cons….Fast forward to today: I am addicted. I can’t function without it. I have tried and can’t go one day without it. My eyesight has suffered I know. Everything is always blurry… I feel spacey all the time. I have gained ALL my weight back and more! I am always VERY angry and easily agitated. I am depressed/crying most of the day – My husband and I are on verge of divorce because the sight of him now just aggravates me to the point that we fight every day. I seem to dwell on all the little things that I can’t stand in everyone. I’m miserable! and making everyone around me miserable… how do I wean myself off!? I have to get my life back!

    • Hi Annie,
      Weening yourself off phentermine won’t be easy judging by the scale of your addiction-related symptoms. You should speak to your doctor to see if there is some way he or she can help you gradually cut down and get your life back. Wishing you the best of luck.
      Sally, phentermine.com

  37. I have been reading a lot and almost all of the comments here. I first started Phentermine February 2001 – May 2001. I weighed in at 187lbs and within months I weighed in at 119lbs. Loved this stuff! Miracle pill I called it. I worked out, ran, cleaned house like no other. Best feeling in the world. Then, I started to have my heart rate at 120 per min just sitting. Started to have anxiety, panic attacks, along with ticks! I started to blink my eyes unctrollably along with stretching my mouth wide open. I couldn’t figure out what the heck was going on and still haven’t until now. Reading some of the posts just made everything clear to me. I became a hypochondriac! Worried about EVERYTHING! Constantly in and out of Dr offices including the ER! I stopped taking this medicine for a while. I had my daughter Sept 2006. Decided to try it again and nope, instant panic. Couldn’t do it. Decided to work out and eat healthy. Lost all my baby weight and felt good about life. Met my now husband 2009. Still working out and couldn’t have felt better about myself ever. I’m fit, beautiful, he’s a muscular man indeed. We were both into fitness and along with that, we enjoyed our wine nights. We found ourselves sitting in the parking lot at the workout center debating on going in or going home tommake dinner and drink. We eventually got into the routine of drinking instead of the gym! Oops, bad, idea! We’re now married since 2011. We have both gained weight! More my husband b/ I have an eating disorder scared out of mind to even admit it! But, I do! I eventually got him started on Phentermine. He lost 20 plus pounds but puts it back on b/ he stops. I have to admit. I have been taking his pills as well. Not experiencing panic attacks but noticed my tick came back with the eyes after consuming the pill. It’s been this way since 2012, 4 years. One other thing I’ve noticed is and I’m sorry to be so informative but. Diarrhea!!!!!! Upset stomach!!!!!! Hemorrhoids!!!!!! Bleeding!!!!!!! Ticks!!!!!!! Anxiety!!!!!! Body aches!!!!!! Need I say more. This medicine may help you suppress your appetite, lose weight, possibly feel good, look good. But it’s doing more harm than good. I have been off for about three weeks and I’m finally noticing why I have had all these health issues. Maybe and more than possible is b/ I have been on it so long. I’m just glad I have finally come to realize I’m really not crazy. Medicine is. 😄👍. Love your body, eat right and listen to it. Took me far too long to do so. God bless

    • Did your anxiety and depression stuff seem to subside after being off the adipex for a while? I’ve been taking it off and on for about 3 years now I’m not addicted by no means bc when I say off and on its on for approximatey 2 to 3 months at a time, anyways about 3 years ago I was diagnosed with severe anxiety disorder and bipolar depression and the anxiety just seems to get worse and worse, well after reading a lot of the comments on here I started to realize I didn’t get this bad amxiety until after I first started taking the adipex…Anyways my anxiety is getting severe again and I just recently started taking the medicine again, and I’m just hoping stopping the adipex for good will help with my severe anxiety… Thanks

  38. I have been on Adipex for 5 days. I have not slept at all. I am nervous and jittery and have no appetite. Called my dr. and they said to split the pill. The dose is 37.5. I weigh 167 right now and am 5’6″. I have lost 3 lbs already. I just wonder whether I really need this pill. I need to be able to sleep. What do you think?

  39. I’ve been taking Phentermine (30mg/qd) for 2 weeks and I was not getting results, perhaps because I’m 40 now and losing weight is harder now. So I added Wellbutrin 300mg/qd and Magic! I feel really good, my mood is improved and I am not eating everything I find. I know that a new behavior (diet/workout) needs to be established for me to succeed after the medication has to stop. Like making new brain connections and also understanding why I over-eat, why I use food to calm my anxiety, or if I’m bored or sad.

  40. I’ve been on and off (mostly on) phentermine for two years. I’ve just recently realized my blood pressure is high. I tried to quit cold turkey but the withdrawal effect was too severe so I cut my dosage from 37.5mg to 30mg. I’m planning to cut down to 1/2 a 37.5mg pill, so like 19mg, soon hoping this won’t cause side effects. I’d really like to get off of it permanently as I believe it is starting to effect my health, plus I don’t think it’s helping me lose weight anymore, but it is so addictive. I’m afraid of the long term health effects, I’m only 24, I should not have high blood pressure. Do you think if I get off the phen soon my blood pressure will return to normal?

    • Hi SDgirl24,
      We’re sorry to hear that your health has suffered after taking phentermine for an extended period but it sounds like you are taking control of the situation by reducing your dosage gradually with the aim of stopping. You would have to check with your doctor about your blood pressure but certainly coming off phentermine will help to improve your overall health.
      Sally, phentermine.com

  41. Hi I have been using this medication for nearly 4 years. At the beginning I used 37.5 dosis to lose the 40 lbs I wanted but then I have been taking only half of this to keep me fit; it helps me not to eat too much as I do without it. Thanks to God that I found this website because the problem is that now I have been feeling pain in my chest, shortness of breath, tachycardia. I was always very healthy so I wonder if these symptoms are because the phentermine. I will make an appt for my doctor ASAP.

    • Hi Yullet,
      From what you say it’s highly likely that the side effects you’re experiencing are a result of phentermine. We would advise you to stop taking phentermine now rather than waiting to speak to your doctor.
      Sally, phentermine.com

  42. I have been on this medicine for two years. It has helped me loose weight and I feel so much better about myself. The only side effect that I have is the dry mouth. I use to have to take medicine for acid reflex but since on the Phentermine I no longer take the omeprazol. My blood pressure is perfect and I do not take blood pressure medicine. This has been a miracle for me.

  43. I\’ve taken Phentermine recently (4 weeks), my weight loss is not significant, however it has reduced my cravings. The most unusual result however is that I sleep better? I take half a pill around 10am, around 2:30 I take a 30 min restful nap. Then easily go to bed around 9pm, aking at 5:30am. Years ago I took Nuvigil prescribed by my sleep doctor. I do not have apnea, I was diagnosed with excessive sleepiness. Nuvigil is no longer available for my condition, she recommended Ritalin, but I passed. I received the Phentermine from a weight loss clinic. This is given me better rest, and better wake cycles, I sleep more restful. Is this been noted before for helping sleep issue patients? I understand some struggle going to sleep, but this helps me sleep better and more restful.

  44. I am a 50 yo female and have taken phentermine on and off for 20 years now with no side affects whatsoever. I do notice that the effects of it have greatly reduced but they still continue to suppress my appetite. This medication is not intended to be stopped abruptly as it will have adverse affects. It is best if you wean off the medication.

  45. I am a type 1 diabetic, I developed it when I was 8. Im now 45 and Ive been on phentermine off and on for probably 5 years. Dry mouth and speed are the two side effects that are worst for me. I go off the medicine for a few weeks when my 30 day prescription runs out because I have gotten so used to it, it stops working with my weight loss efforts. The lazy feeling that comes with stopping is almost unbearable. I wonder about the long term with my heart and I see where some people have developed vision problems. Is vision loss a side effect of phentermine? BTW, Istarted phen to lose weight. Im still 200 +, it only allows me to maintain my weight. I keep hoping stopping/starting will help me, it never has. I hike at least 20 miles a week, I eat right and exercise. I dont know if the side effects are worth the energy boost and hopefullness of losing weight. Wish it worked for me better. Not real sure what to do.

  46. I have long term experience with Phenterminel on and off for over 20 years. I admit dependence, however I have stopped when they were no longer effective. My doctor monitors me closely, and if I were not able to get them, I fear what alternative I might take, since I was an amphetamine user in my teens. I am now age 50, my blood pressure is outstanding, and have no major health issues. In fact I worry what would happen if I stopped.

  47. I have been on Phentermine 37.5mg capsule since 2003. I have taken a few breaks over the years but not more than 6 months before needing to go back on it. My story a little different from most here. I have been a fitness pro for over 25 yrs. From 1999 – 2002 I\’d began to gain weight and experience extreme lethargy to the point I\’d get nauseous. Long story short, went to many dr\’s when an endocrinologist sent me to have a true metabolic study done. By this time I\’d gone from 120lbs to 150lbs and that was with 2 work outs a day, plus training clients and eating down to 1200 Cal a day.

    Study came back I was only burning 890 Cal a day even w/ my muscle mass. I also had low heart rate, BP & body temp. Dr said my central Nervous system was almost dormant and started me on phentermine. It worked as weight started coming off, I could stay awake and not get nauseous from fatigue and my mood improved (well I was extremely depressed being a trainer w/ a weight problem)

    I got breast cancer in 2008 and was off them for about 9 months. Then all the symptoms crept back. Went off again in 2013 for about 6 months and symptoms came back.

    While taking them my HR stays mid 60\’s, BP hangs around 100/70 and body temp 97.9- 98.1. I have had a few echo cardiograms over the years w/ my latest one two weeks ago, all normal. Biggest side effect is dry mouth and blood pressure drops when I stand up too fast (but that happened before)

    However, I was recently diagnosed w/ lupus and am undergoing additional tests as it seems to have attacked my lungs & kidneys. I have a team of three dr\’s: internist, endocrinologist & rheumatologist. Internist says adverse affects of phentermine. Endo & rheumatologist says not related at all. But I\’ve just started this new journey so I suppose I must consider all possibilities.

  48. I started taking phentermine in 2008 before I had my first son. I lost weight quickly and felt great. There was a sudden \” speed\” like effect I experienced for the first couple of weeks but that wore off. I took it for about 6 months. Then I became pregnant. Few months after giving birth I got back on it. Worked just like the first time. Lost weight quickly. I was on it the 2nd time for about 1 year , maybe 1 year and a half. Then I became pregnant with my 2nd child in 2011. About 5 months after giving birth I got back on it to lose the baby weight. This 3rd time I was on it for about 6 months this to a year give or take. Had no problem losing the weight and kept it off until I became VERY sick in 2015 while taking it. Long story short I found out I had Myasthenia Gravis disease. Affects all your voluntary muscles. First one in my family to have anything like this. It interferes with transmission of signals from your brain to your muscles. I quit taking while I was sick. Skip forward to present day. I got a month supply since I have gained weight from the steroids I had to take while sick and actually being able to eat. Mind you I have been in remission of MG the last 2 years. Well upon taking phentermine currently I\’ve noticed my MG symptoms come back. A doctor has not confirmed with but in the back of my mind I feel phentermine has caused the Myasthenia Gravis. Please beware of long term effects. You don\’t want to end up with a life long incurable illness for a quick fix of weight loss. Completely not worth it. I almost lost my life when I was sick.

  49. I\’ve been on phentermine consistently since 2011 only stopping for the 9 months I was pregnant. Only side effects I\’ve noticed is the dry mouth as sell as more difficulty falling asleep. It still curbs my appetite and gives me the boost of energy. It puts me in a better mood and makes me feel like I wanna get things done. Lately I\’ve been noticing I feel short of breath and can\’t hold my breath for as long as I could before. Wondering if that has anything to do with the phentermine and if anyone has experienced the same problem. Any feedback will helpful and greatly appreciated!!!

    • Hi Shari! Shortness of breath can indicate a serious phentermine side effect, so we would recommend speaking with your prescribing doctor about this ASAP. It may also be caused by something else, but your doctor would be best able to determine why you’re having trouble holding your breath and help you solve it.
      Rachel, phentermine.com

  50. Ok so my dr prescribed me phentermine 3 months ago and I have lost about 40 pounds but I’m not to my target weight. I was 180 pounds at 5’3” and now I’m 141, I was hoping to get to 125. Anyway Rx is about out and dr told me I’m on my own. Problem is it has helped my depression, RA and Fibro SO much like no other med and I’m afraid not only to gain the weight back but to get depressed and have pain again. What do I do now??? It may be addicting but he won’t prescribe it so what do I do now?

    • Hi Tracey! We would suggest speaking with your prescribing and/or primary care doctor about the other benefits you’ve seen while taking phentermine, and asking if there is an alternative medication that he or she could recommend. While it’s not advisable to take phentermine long-term, there may be other options that could help manage your depression and pain similarly. Best of luck!
      Rachel, phentermine.com

  51. I began a successful phentermine journey in 2011. Phen was prescribed by my family med doc for a duration of 7 months. During this time I lost 50 lb\’s. It was a great experience and I kept the weight off for close to 4 years. I started having issues due to pre-menopause and my doc started me on zoloft and then prozac.
    though I continued to monitor my eating habits, and exercised 3x per week, the weight kept coming on. My doc checked full blood panel. Her only suggestion to the weight gain was the use of the anti-depressants.
    In early Feb of 2016 the same doctor put me back on the phen. i busted my ass to lose the weight, but it was coming off VERY slowly. I feel much better, Im even more active, my blood pressure has gone down, and I have lost 26 lb\’s.
    Unfortunately, change in insurance caused my providers to be changed. I was with Sutter but now a clinic based provider. My doctor of 20 years wrote up a full description of me. it directed my new doctor to continue the phen throughout December of 2017, discuss the possibility of change in anti-depressants, and taper down phen throughout a months time till I depend on myself for eating and workout habits to continue. My doctor also documented that the new provider continue to monitor my weight as she had done.
    Yesterday I saw my new provider for the first time. He was very rude! He ordered me off of the phen immediately without tapering me and lectured me about the risks of the medicine. He then said he was ordering an echo cardio gram. He also took me off of my current anti-depressant of prozac, because again, \”he didnt approve\”.
    Im nervous about the expertise and opinion of this new physician. Also about gaining the weight back and not feeling as good. I worked hard, and was looking forward to reaching my goal, and continue monitoring my health & weight.
    Any sugesstions?

    • Hi Teena!

      Doctors have the final word regarding advice on phentermine use and other medications. That being said, if you do not feel comfortable with any doctor, you can look for a second opinion too. Best of luck!



  52. Hello
    I\’m 32. Have been on adipex about 5 weeks. Ive taken it before, a few yrs ago, but got pregnant (long after I stopped taking the med) and have had trouble getting back into shape. I don\’t take it every day because I work night shifts 3 days a week, but stay up during the day when I don\’t work. I started taking it now to help with energy to work out. I have energy troubles due to my work schedule. I\’ve not experienced any of the side effects I did last time, insomnia, palpitations, etc. I have a slight reduction in my appetite, but nothing like last time I took it, thankfully. The first time the idea of any food was appalling. However now I\’m not getting much energy boost, after only 5 weeks. Just wondering, since I\’m not experiencing any side effects, no increased heart rate or BP, no palpitations, or high blood pressure, nothing but maybe slight indigestion sporadically, what risks would I be taking if I took it every 12 hrs once or twice a week? I wouldn\’t run out bc as I said, I don\’t take it every day. For instance, if I took my meds at 5pm yesterday, would taking one or a half tab at 8 am the following day pose any risks to my health? My prescription is the 37.5mg

    • Hi!

      For ANY change in dosage, or adding any additional medicines, drugs or supplements of any type while taking phentermine, we STRONGLY suggest talking to your prescribing doctor. Although it is good that you’re not having any of the nasty side-effects of the first time, you’re still taking a very powerful drug at the highest legal dosage. Consult with your doctor first to see what are your options.



  53. I started about 9 months ago and it worked so well. I have sleep apnea and was about 100 pounds over weight. I have major food cravings and drink alcohol on weekends that contributes to my weight. I had so much more energy taking Adipex and was almost never hungry. I ate eggs in the morning, veggies for lunch, and a piece of meat for dinner. I exercised a few times a week, but suddenly had energy to run on the treadmill. I lost 40 pounds over four months. My doctor said I had to switch off of it so I went on Contrave. I maintained the same diet, but had less energy to exercise. I gained back 10 pounds during the 3 months of Contrave. My cravings were slightly less than normal on Contrave, but I felt like I had no metabolism or energy. Started my second round of Adipex this month.

  54. I’m a 30yo female and I’ve been taking Phentermine on and off for almost 10yrs now. The only side effects I’ve noticed are dry mouth and dry eyes. I’ve noticed it doesn’t necessarily help me lose weight anymore but it does control my appetite and wakes me up better than coffee. When I stop taking it I might as well have narcolepsy. I take it mainly to maintain my weight and wake up to function. I haven’t noticed any problems when stopping the medication other than tiredness and wanting to inhale any food in sight. I am concerned about long term effects of the medication because hypertension and heart disease runs in my family. I will admit a dependence to it because it’s convenient and the energy it gives me. Any recommendations to break the dependence for good?

    • Hi Carolina, thanks for your comment! We would suggest speaking to your doctor. He or she can work with you to reduce usage and ultimately get off phentermine. The fact that it no longer helps you lose weight is another indication that your body has developed a tolerance to the medication. Still, you’re wise to be concerned about the long-term effects of staying on phentermine and you’re awareness of the dependence means that you’re already moving in the right direction. So, we would suggest a doctor’s visit as the next productive step. Best of luck!
      Rachel, phentermine.com

  55. I was on this medicine phentermine 37.5 for 5 1/2 years straight. Never came off of it took it every day and I can honestly say that i never abused this medicine not one time. I took it like I was surposed too. I\’m off of it now but it done alot of damage to my body over the 5 1/2 years I took it. I will never ever take this medicine again. I just hope anyone who is on this medicine I pray you get off of it. It\’s very bad for you. There\’s other ways to loose weight.

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