The Ultimate Guide to Over-the-Counter (OTC) Phentermine

The popular weight loss medication phentermine cannot be bought over-the-counter (OTC) because it requires a prescription. However, you can buy effective over-the-counter diet pills similar to phentermine without seeing a doctor.

Phentermine OTC

Too busy for the full read? Here’s what you need to know:

  • Buying phentermine over the counter is not possible.
  • Phentermine is a class IV controlled substance due to its risk of addiction and serious side effects.
  • You can purchase alternative weight loss supplements without a prescription.
  • Supplements may have no side effects and can be taken long-term.
  • Unlike phentermine, OTC diet pills are not monitored by a doctor.
Phen Caps
Best for Appetite Suppression

Phen Caps


✅ Suppresses appetite
✅ Boosts energy levels
✅ All-natural ingredients
✅ No negative side effects
✅ Over 35,000 customers
✅ Real testimonials

❌ May interfere with sleep if taken in the evening

5 Star Fat Burner
Best Fat Burning

5 Star Fat Burner


✅ Increases metabolism
✅ Burns fat
✅ Controls hunger
✅ 100% natural
✅ No caffeine
✅ Vegetarian

❌ Lack of caffeine may mean energy levels do not feel boosted

KETO Charge
Best with Keto Diet

KETO Charge


✅ Helps your body reach ketosis more quickly
✅ Aids fat burning
✅ Avoids keto flu
✅ Boosts energy
✅ Once daily capsule

❌ Works best with a keto diet
❌ Not suitable for vegetarians or vegans

Phen Q

Phen Q


✅ Burns fat
✅ Suppresses appetite
✅ Blocks fat production
✅ Boosts energy levels
✅ Enhances mood
✅ Vegan

❌ May interrupt sleep if taken after 3pm

Can You Get Phentermine Over-the-Counter?

No, buying phentermine over the counter is not possible as it is a class IV controlled substance. Branded versions of phentermine, including Adipex-P, are also subject to the same prescribing rules of the Controlled Substances Act (CSA).

The Controlled Substances Act is regulated by the United States Drug Enforcement Administration. Its role is to determine how medications should be accessed based on the likelihood of addiction, dependence, or abuse ( 1 ).

As phentermine has a similar chemical structure to amphetamines, there is a risk of dependence. For this reason, in most cases, phentermine is only prescribed for three months at a time.

Phentermine can also cause a range of common and serious side effects, such as headaches, dry mouth, mood changes, and hallucinations. It is, therefore, not considered safe to buy phentermine or Adipex over the counter ( 2 ).

Related: Side Effects of Phentermine

Prescription Phentermine vs. Over-the-Counter Alternatives

The good news is many over-the-counter phentermine alternatives do not require you to consult a doctor for a prescription.

However, there are differences between prescription phentermine and over-the-counter diet pills.

Key Differences

Unlike phentermine, over-the-counter diet pills can be purchased without a prescription from CVS, Walgreens, and even Amazon, making them a convenient choice. There’s no need to speak to a doctor or pharmacist; you can often have the pills delivered to your door whenever you need them.


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Whereas Adipex-P has a long list of irritating, and in some cases, serious, side effects, over-the-counter equivalents to phentermine may have no side effects at all. For this reason, if you find that an OTC weight loss pill is helpful, you may be able to take it long-term rather than being limited to three months as with phentermine ( 3 ).

Compared to phentermine, over-the-counter diet pills can help you lose a similar amount of weight. Using natural ingredients, weight loss supplements promote fat burning while reducing the appetite and boosting energy levels. Unlike phentermine, weight loss is achieved without the risk of side effects or the potential for addiction ( 4 ).

Who Should Consider OTC Alternatives?

You may consult a doctor and find that, based on your weight and medical background, they are willing to prescribe phentermine for you. However, many people eligible for a phentermine prescription choose to take an alternative instead. For example, you may prefer to try an over-the-counter diet pill to focus on losing weight without worrying about serious side effects or the potential for addiction.

Some people cannot take phentermine because they have conditions including heart disease, high blood pressure, diabetes, or a history of addiction. In this case, an over-the-counter equivalent to phentermine may be recommended. Alternative weight loss pills can help reduce the appetite and burn calories without putting your health at risk.

Top Over-the-Counter Phentermine Alternatives

Many diet pills are available, each promoting weight loss in a different way. There are four great OTC alternatives to phentermine.

Phen Caps

Phen Caps are taken twice daily for an average weight loss of around 1-2 pounds per week, giving similar results to prescription phentermine. The natural ingredients suppress the appetite, boost energy levels, and burn calories. This makes it easier to eat less and exercise more to lose weight more quickly ( 4 ).

Ingredients: Phenylethylamine, Caffeine, Theobromine, Caralluma, Synephrine, L-Carnitine, Raspberry Ketone, Chinese Hawthorne Berry Extract, and Selenium.

Best Appetite Suppression
Phen Caps
9.4/10Our Score
  • Suppresses appetite
  • Boosts energy levels
  • All-natural ingredients
  • No negative side effects
  • Over 35,000 customers
  • Real testimonials
  • May interfere with sleep if taken in the evening

5 Star Fat Burner

5 Star Fat Burner is an all-natural capsule that promotes fat burning 24/7. It contains Capsimax and GreenSelect Phytosome, which have been proven to increase calorie burning. In clinical trials, participants taking the active ingredients showed significant weight loss results compared to those taking a placebo ( 5 ).

Ingredients: Capsimax, Greenselect Phytosome, Raspberry Ketone, Pomegranate Seed Extract, Chromium, Oligofructose, and Griffonia simplicifolia plant (5-HTP).

Best for Fat Burning
5 Star Fat Burner
9.1/10Our Score
  • Increases metabolism
  • Burns fat
  • Controls hunger
  • 100% natural
  • No caffeine
  • Vegetarian
  • Lack of caffeine may mean energy levels do not feel boosted

KETO Charge

KETO Charge capsules are designed to help those trying to lose weight when following a keto diet. The nutrients make it easier to reach ketosis and help to manage symptoms of keto-flu associated with a high-fat, low-carb diet. Fat burning is promoted, and you may feel more energetic ( 6 ).

Ingredients: Magnesium Beta Hydroxybutyrate, Calcium Beta Hydroxybutyrate, Sodium Beta Hydroxybutyrate, Gelatin, and Rice flour.

Best With Keto Diet
KETO Charge
8.7/10Our Score
  • Helps your body reach ketosis more quickly
  • Aids fat burning
  • Avoids keto flu
  • Boosts energy
  • Once daily capsule
  • Works best with a keto diet
  • Not suitable for vegetarians or vegans


PhenQ is a vegan-friendly natural capsule that has no side effects. It burns fat, controls the appetite, and boosts energy levels to help you lose weight. It can be taken indefinitely to aid weight loss and help you maintain your target weight ( 7 ).

Ingredients: Capsimax, Chromium Picolinate, Caffeine, Nopal Cactus, L-Carnitine Fumarate, Innoslim, B-Vitamins, and Iodine.

8.3/10Our Score
  • Burns fat
  • Suppresses appetite
  • Blocks fat production
  • Boosts energy levels
  • Enhances mood
  • Vegan
  • May interrupt sleep if taken after 3pm

What to Consider Before Taking OTC Diet Pills

Although diet pills can be bought without seeking medical advice, it is still important to do some research before you start a new weight loss supplement.

Despite containing natural ingredients, diet pills are often contraindicated for individuals under 18, and pregnant or breastfeeding women.

If you have a medical condition or take any other prescribed, over-the-counter or herbal medications, you should speak to your doctor or pharmacist to check that the diet pill will suit you.

Taking over-the-counter phentermine alternatives can be safer than taking phentermine. Still, it is important to remember that, unlike phentermine, supplements are not monitored by a doctor. If you have concerns, you should consult a trained healthcare professional.

The final consideration is that while many diet pills have shown promise in clinical trials, the best weight loss outcomes are always achieved when supplements are taken in conjunction with a calorie-controlled diet and increased physical activity. It is therefore essential to also make lifestyle changes.


It is not possible to buy phentermine over the counter. Still, you can purchase various alternative weight loss supplements without a prescription. Natural supplements can suppress the appetite and boost fat burning for increased weight loss without the severe side effects of phentermine.


Where can you get phentermine over the counter?

Phentermine cannot be bought without a prescription because it is a controlled substance.

However, a range of effective, over-the-counter diet pills similar to phentermine can be bought without seeing a doctor or getting a prescription.

Can you get Adipex over the counter?

No, you cannot get Adipex over the counter. Adipex is a branded version of phentermine, and as phentermine is a class IV controlled substance, it is not possible to buy Adipex or generic phentermine without a prescription.

Are over-the-counter phentermine alternatives safe?

You may choose a diet pill containing natural ingredients because you want a safer way to lose weight or wish to avoid side effects. However, some diet pills are not suitable for under-18s, pregnant women, or those with pre-existing medical conditions.

You must read the label and consult your doctor or pharmacist if you need help determining whether a medication is safe for you.

Can I take over-the-counter phentermine alternatives with other medications?

If you take other medications, it is essential to always check with your doctor before you start taking a diet pill or any other new supplement.

How long should I use an over-the-counter phentermine alternative?

Unlike phentermine, over-the-counter diet pills can often be taken for as long as they continue to help you lose weight.

While phentermine can only be taken for three months at a time, some people take natural weight loss supplements indefinitely to promote weight loss and maintain their target weight. Always read the label to check how long you can take a supplement.

Can I use multiple over-the-counter alternatives at once?

No, it is best only to take one phentermine alternative at a time. If one supplement does not have the desired effect, stop it and try a new one.

Once you have found the right diet pill, persevere with a calorie-controlled diet and increased physical activity for maximum weight loss.

  1. Drug Enforcement Administration (2018). The Controlled Substances Act
  2. Kim, K. K., Cho, J., Kang, C., Youn, B., & Lee, R. (2006). Effects on Weight Reduction and Safety of Short-Term Phentermine Administration in Korean Obese People. Yonsei Medical Journal47(5), 614-625.
  3. What is Phentermine? (2023)
  4. (2023)
  5. 5 Star Fat Burner (2023)
  6. Keto Charge (2023)
  7. PhenQ (2023)