By Dr. Karen Viera - Last updated Sept. 3, 2018
Adipex is the most popular brand of phentermine in the United States.
This prescription-only medication supports weight loss by suppressing appetite and increasing energy. In combination with healthy diet and exercise, it can help you transform your lifestyle and reach your weight loss goals faster.
TABLE OF CONTENTS
Here is the basic information you need to know about Adipex weight loss pills: what they contain, what they look like and how they work.
The active ingredient in Adipex diet pills is phentermine hydrochloride (phentermine HCL). Each pill contains 37.5mg of phentermine HCl, which is equivalent to 30mg phentermine base.
This prescription appetite suppressant is available in tablet and capsule form.
The inactive ingredients in Adipex tablets include: corn starch, lactose (anhydrous), magnesium stearate, microcrystalline cellulose, pregelatinized starch, sucrose and FD&C Blue #1. The capsules’ inactive ingredients are: corn starch, gelatin, lactose monohydrate, magnesium stearate, titanium dioxide, black iron oxide, FD&C Blue #1, FD&C Red #40 and D&C Red #33 [A].
Adipex tablets are blue and white with an oblong shape. Each tablet is scored and embossed with "ADIPEX-P" and "9-9". Each bottle contains 30 tablets.
Adipex capsules are opaque capsules that are half bright blue and half white, with two dark blue stripes around the white end. Each capsule is imprinted with "ADIPEX-P" and "37.5". The capsules are packaged in bottles of 100.
Phentermine hydrochloride is a sympathomimetic amine that stimulates the nervous system to promote weight loss .
It promotes the release of norepinephrine: a neurotransmitter that triggers “fight or flight” to increase energy and reduce hunger . It also stimulates the release of adrenaline (epinephrine) to other areas of the body, which leads to the breakdown of stored fat .
Similar to other weight loss medications, Adipex works best when combined with a healthy diet and regular exercise.
Good to Know
Adipex is a short-term treatment for exogenous obesity.
This type of obesity can occur from eating too much, moving too little, or a combination of the two. Phentermine is not designed to treat obesity caused by other medical problems.
Adipex is an option for patients with a body mass index (BMI):
Still, Adipex is not appropriate or safe for everyone – even within these BMI ranges [A].
Read more here: Phentermine Precautions
The standard dose of Adipex is 37.5 mg once per day.
Alternatively, some users split their Adipex tablets in half. These patients may take just one half of the pill (18.75 mg) each day, or split the tablet to take the two half doses at different points during the day. The second option is a common strategy for people who struggle with afternoon or nighttime cravings.
Phentermine is designed as a short-term treatment for obesity, so it should not be taken for more than 12 weeks at a time. If your doctor believes that you could benefit from a longer treatment period, he or she can weigh the pros and cons of prescribing Adipex (phentermine) off-label for longer.
Overdosing on phentermine is dangerous. Taking more medication than prescribed does not increase effectiveness and can have serious, potentially-fatal, consequences.
Learn more here: Phentermine Overdose
Adipex is highly effective for weight loss, but it can also cause many side effects - ranging from relatively mild to undeniably severe. While some people experience intense reactions, others have no side effects at all.
The most common Adipex-P side effects are:
Side effects are typically most severe at the start of treatment, as the body works to adjust to phentermine.
Below are the percentages of current users who have experienced phentermine’s most common side effects, as reported in a recent online poll:
Although less common than the reactions listed above, severe side effects of Adipex are dangerous and potentially life-threatening.
Symptoms of a severe reaction to phentermine include:
Like with any drug, it is possible to have an allergic reaction to Adipex-P.
Signs of an Adipex allergy include:
If you or someone you know experiences any of these symptoms while taking Asipex, seek medical attention right away.
Adipex 37.5 mg should be taken once daily on an empty stomach: either 30 minutes before breakfast or 1-2 hours after eating.
Do not take this medication late at night or just before bed because it can cause insomnia.
If you have an atypical sleep-wake schedule (such as shift work) that makes early-morning dosing disadvantageous, discuss an individualized phentermine schedule with your doctor at the initial appointment.
NEVER adjust Adipex dosage or schedule without talking to your doctor and pharmacist first.
The best Adipex diet is a balanced eating plan that you can maintain over the long term.
While it may be tempting to jump into the latest fad diet or slash calories dramatically to lose weight quickly, avoid extreme diets unless they are specifically recommended & supervised by your doctor. Instead, take advantage of the medication’s appetite-suppressing power to incorporate more healthy eating habits – like portion control and getting your “5-a-day” of fruits and vegetables – into your daily routine.
There is no specific or perfect “Adipex diet”, but consistently eating healthy portions nutritious meals will help you lose and maintain weight.
Adipex suppresses appetite, curbs cravings and increases energy to help patients lose weight quicker and easier [1, 4, 9].
Average weight loss on Adipex, and phentermine in general, is around 1-4 pounds per week.
Here are the inspiring Adipex weight loss stories of two real women:
Starting Weight: 204 lb | Current Weight: 149 lb | POUNDS LOST: 55
Kristin embarked on her weight loss journey to get healthy for herself and her daughter. After losing over 50 pounds, she loves shopping for smaller clothes
Starting Weight: 230 lb | Current Weight: 184 lb | POUNDS LOST: 46
Neva asked her doctor about Adipex after being diagnosed with high blood pressure, and – soon after – type 2 diabetes. She hated having to throw away all of her expensive clothes as she lost weight, but now she loves being to slip into the same size dress she wore at her wedding!
Looking for more inspiration? Click here to browse more phentermine success stories!
Over the past fifteen years, hundreds of phentermine users have submitted their Adipex reviews, successes and struggles. Browse through the entries below to learn how real patients feel about these famous weight loss pills.
Phentermine is a controlled substance, so the only way to buy Adipex legally is by filling a doctor's prescription at a DEA-registered pharmacy.
Yes, phentermine is class IV controlled substance in the US and abroad . Sale and distribution of Adipex is closely monitored and controlled.
Yes. Due to its chemical similarity to amphetamines, phentermine can produce a false-positive for amphetamines (meth) on a standard drug test . However, phentermine is NOT an amphetamine.
Expect phentermine to appear on a urine drug screen for 4-7 days after your last dose of Adipex . You may test positive for longer if you have been taking phentermine for a long time or at higher-than-normal doses.
Good to Know
Adipex-P is the most well-known brand of phentermine in the US, but that doesn’t mean it is the only option.
One of the most common questions people ask is, “Is Adipex phentermine?” The answer is yes –Adipex is a popular brand of phentermine diet pills.
If you’re comparing phentermine to Adipex, you are comparing a brand name pill to the generic form of the same medication. Generic phentermine is typically cheaper and available in a wider variety of doses.
Contrave contains a combination of naltrexone and bupropion extended-release to suppress appetite and control cravings [2,6]. It can be taken for longer than Adipex-P and it is not a controlled substance, but the weight loss pills can cause a variety of serious side effects.
Bontril is a popular brand of phendimetrazine, another drug that promotes weight loss.
It's similar to Adipex in that both medications act as central nervous system stimulants, and are both controlled substances . However, patients respond to these two drugs very differently and some individuals experience better outcomes with Bontril.
Didrex is the brand name for the benzphetamine: another prescription appetite suppressant. Similar to Adipex and Bontril, Didrex decreases the appetite and boosts energy by enhancing the activity of the central nervous system .
Didrex is a higher, class III controlled substance, but Adipex is more potent.
As an over-the-counter alternative to Adipex, Phentermine.com recommends Phen Caps.
These powerful supplements contain nine all-natural ingredients that suppress the appetite and boost energy, without the side effects. They do not contain any phentermine HCl, which means that Phen Caps are legally available online and without a prescription.
Adipex diet pills are manufactured by Gate Pharmaceuticals, a subsidiary of Teva Pharmaceuticals USA. They have been producing and marketing this diet pill since 1990.
The contact information for GATE Pharmaceuticals is:
Teva North America
1090 Horsham Road
North Wales, PA 19454 USA
Tel: 888-TEVA-USA (888-838-2872)
1. U.S. Food and Drug Administration. (2012). Adipex-P (phentermine hydrochloride) capsules label [Brochure].
4. Food and Drug Administration, Washington (USA): QSYMIA (Phentermine HCL and Topiramate), Application number: 22590Orig1s000, Clinical Pharmacology and Biopharmaceutics Review.
5. National Center for Biotechnology Information. PubChem Compound Database: CID=4771 (Phentermine).
7 - 8. National Center for Biotechnology Information. PubChem Compound Database: CID=12460 (Phendimetrazine).
8 - 9. National Center for Biotechnology Information. PubChem Compound Database: CID=11558159 (Benzphetamine HCl).
9 - 10. Weintraub M, Hasday JD, Mushlin AI, Lockwood DH. A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination. Arch Intern Med. 1984;144(6):1143-1148.
Dr. Karen Vieira has a Ph.D. in Biomedical Sciences from the University of Florida College Of Medicine. She has worked in hospitals conducting clinical research with patients, as well as in the food industry where she researched food and supplement ingredients for a variety of health conditions.