I have been taking it for two weeks now. Yes there are side effects if you ate to much fat. I have been on a low fat diet for 6 weeks now and have lost 12 pounds so far. I feel it is still worth taking even if you are on a low fat diet. It is working for me. I also go to the gym 5-6 days a week. I have gone out to dinner 3-4 times since starting this diet and ate more fat then I do every day, I was glad to have the xenical I felt it help me not to gain back any of the pounds I lost. IT is still going to take time and afort to reach my goel of 120 pounds, I feel that this will help me get there. It won't stop you from eating fat :p , but when you do you will know that not all of it is going to your hips. Some people told me it can be cobined with Phen ? Any risk to do that? :confused: