A particularly significant study entitled "Dietary Conjugated Linoleic Acids Increase Lean Tissue and Decrease Fat Deposition in Growing Pigs" was published in the November 1999 issue of the Journal of Nutrition. The key element of the study was the confirmation that CLA is able to decrease fat storage and maintain lean muscle tissue. In this study, researchers used young female pigs to illustrate the effects of combining a relatively small amount of CLA with the pig's normal diet. Pigs have organs and metabolisms similar to humans, so they are good experimental models for human nutrition. Sixty pigs were randomly placed in one of six dietary treatments, one being the control group that received no CLA. Each other group received one of five different concentrations of CLA added to the animals' feed. The pigs had free access to water and their diet at all times (two kilograms of food per day).
After just four weeks of CLA supplementation, there was significantly less fat and more lean tissue in the groups receiving the CLA. After eight weeks, the pigs with the highest CLA supplementation showed a 31% loss of body fat and a 5% increase in lean tissue. In addition, at the highest level of CLA supplementation, the back fat depth was reduced by 25%. This study was the first to show the profound effects of CLA supplements on the composition and deposition of body fat, in relation to protein, water and other pig tissues.[10]
A study published in the August 2001 issue of the International Journal of Obesity and Related Metabolic Disorders concludes that conjugated linoleic acid (CLA) reduces abdominal fat among men classified as abdominally obese. The study participants taking CLA lost an average of 1.4 cm in waist circumference after only four weeks.
This double blind, randomized, placebo-controlled trial observed 25 men with significant abdominal fat for four weeks. Fourteen received 4.2 grams of CLA per day, while the others received placebo. At the conclusion of the study, there was a significant decrease of abdominal diameter among the CLA group. None of the study participants changed their eating or exercise habits during the trial period.[11]
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