Meridia controls appetite just as phen does. the active ingredient is sibutramine and works in the area of the brain that signals a sense of fullness (that didn't work well for me like phen does) Xenical is the medication that works the same as alli allowing your body to get rid of a certain amount of fat and that is why when taking xenical or alli you need to watch your fat intake. I have also taking alli and had no problems but was only losing about .5lb a week.