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I was on Xenical for awhile and have to say I only had problems with it when I ate something with a high fat content which was rare. Some people complain about all of the "ickiness" that they experience and I wonder what they're eating? It is meant to be consumed on a low fat diet.
The drug stays in your system for about 48-72 hours, so even if you skip it during a meal, you'll still have some in your system and may lose the effects at a later meal. If you know you have a big thing coming up that you'll be eating a high fat meal for, stop taking it for a few days so you don't have those side effects.
I am going back on it without hesitation.
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